diff --git a/xen/arch/x86/hvm/hvm.c b/xen/arch/x86/hvm/hvm.c
index 73d1cf0291..36699b861e 100644
--- a/xen/arch/x86/hvm/hvm.c
+++ b/xen/arch/x86/hvm/hvm.c
@@ -2477,6 +2477,9 @@ static enum hvm_copy_result __hvm_copy(
         return HVMCOPY_unhandleable;
 #endif
 
+    if ( unlikely(curr->arch.hvm_vcpu.cache_mode == NO_FILL_CACHE_MODE) )
+        curr->arch.hvm_vcpu.hypervisor_access_uc_hvm_memory = 1;
+
     while ( todo > 0 )
     {
         count = min_t(int, PAGE_SIZE - (addr & ~PAGE_MASK), todo);
@@ -2588,6 +2591,9 @@ static enum hvm_copy_result __hvm_clear(paddr_t addr, int size)
         return HVMCOPY_unhandleable;
 #endif
 
+    if ( unlikely(curr->arch.hvm_vcpu.cache_mode == NO_FILL_CACHE_MODE) )
+        curr->arch.hvm_vcpu.hypervisor_access_uc_hvm_memory = 1;
+
     while ( todo > 0 )
     {
         count = min_t(int, PAGE_SIZE - (addr & ~PAGE_MASK), todo);
diff --git a/xen/arch/x86/hvm/vmx/vmx.c b/xen/arch/x86/hvm/vmx/vmx.c
index 75be62eec0..a0ad37ac3d 100644
--- a/xen/arch/x86/hvm/vmx/vmx.c
+++ b/xen/arch/x86/hvm/vmx/vmx.c
@@ -2974,6 +2974,13 @@ void vmx_vmenter_helper(const struct cpu_user_regs *regs)
     struct hvm_vcpu_asid *p_asid;
     bool_t need_flush;
 
+    /* In case hypervisor access hvm memory when guest uc mode */
+    if ( unlikely(curr->arch.hvm_vcpu.hypervisor_access_uc_hvm_memory) )
+    {
+        curr->arch.hvm_vcpu.hypervisor_access_uc_hvm_memory = 0;
+        wbinvd();
+    }
+
     if ( !cpu_has_vmx_vpid )
         goto out;
     if ( nestedhvm_vcpu_in_guestmode(curr) )
diff --git a/xen/include/asm-x86/hvm/vcpu.h b/xen/include/asm-x86/hvm/vcpu.h
index 8fa5452ab1..a309389187 100644
--- a/xen/include/asm-x86/hvm/vcpu.h
+++ b/xen/include/asm-x86/hvm/vcpu.h
@@ -167,6 +167,7 @@ struct hvm_vcpu {
 
     /* Which cache mode is this VCPU in (CR0:CD/NW)? */
     u8                  cache_mode;
+    bool_t              hypervisor_access_uc_hvm_memory;
 
     struct hvm_vcpu_io  hvm_io;